Senior Bioinformatician, Center for Quantitative Scienc
Location: Nashville, Tennessee
Academic / Research
Internal Number: 2112756
Perform research of a highly complex nature. Lead research projects and perform near to totally independent research. Exercise discretion and independent judgment to develop design of research to test hypotheses. Devise new or modify existing methods and develop procedures to meet new conditions. Effective communication skills as well as efficient data administration and bioinformatics analysis competencies are critical to the success of this position because they will be used in establishing procedures, writing specifications, programming, documenting, and analyzing data, and preparing manuscripts for presentation and publication.
About the Department:
The mission of the Vanderbilt Center for Quantitative Sciences (CQS) is to coordinate and integrate the work of Vanderbilt University and Medical Center quantitative scientists across the disciplines of biostatistics, bioinformatics, biomathematics, computational biology, biomedical engineering, and other related fields, with the end goal of building bridges and streamlining quantitative collaboration for improved biomedical research. CQS members have expertise in basic science as well as clinical/translational studies, with a particular interest in high-dimensional data, including proteomic, genomic, lipidomic, and metabolomic research. The center is available to all university and medical center investigators, offering collaborative support spanning traditional statistical inputs (e.g., experimental design, sample size determination, power analysis, conventional data analysis and results interpretation), to novel statistical and bioinformatic approaches for modern technologies (e.g., advanced sample size determination for next-generation sequencing, multivariate modeling for high-dimensional data), to systems and computational biology approaches for asking questions and modeling results.
Full Time/Exempt Position
Click here to view how Vanderbilt Health employees celebrate the difference they make every day:
Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient care, VUMC is a community of individuals who come to work each day with the simple aim of changing the world. It is a place where your expertise will be valued, your knowledge expanded and your abilities challenged. It is a place where your diversity -- of culture, thinking, learning and leading -- is sought and celebrated. It is a place where employees know they are part of something that is bigger than themselves, take exceptional pride in their work and never settle for what was good enough yesterday. Vanderbilt's mission is to advance health and wellness through preeminent programs in patient care, education, and research.
VUMC Recent Accomplishments
Because we are committed to providing the best in patient care, education and research, we are proud of our recent accomplishments:
* US News & World Report: #1 Adult Hospital in Tennessee and metropolitan Nashville, named to the Best Hospitals Honor Roll of the top 20 adult hospitals, 10 nationally ranked adult specialty programs, with 3 specialties rated in the top 10 nationally, Monroe Carell Jr. Children's Hospital at Vanderbilt named as one of the Best Children's Hospital in the nation, with 10 out of 10 pediatric specialties nationally ranked.
* Healthcare's Most Wired: Among the nation's 100 "most-wired" hospitals and health systems for its efforts in innovative medical technology.
* Becker's Hospital Review: named as one of the "100 Great Hospitals in America", in the roster of 100 Hospitals and Health Systems with Great Oncology Programs and to its list of the 100 Hospitals with Great Heart Programs.
* The Leapfrog Group: One of only 10 children's hospitals in the to be named at Leapfrog Top Hospital.
* American Association for the Advancement of Science: The School of Medicine has 112 elected fellows
* Magnet Recognition Program: Received our third consecutive Magnet designations.
* National Academy of Medicine: 22 members, elected by their peers in recognition of outstanding achievement
* Human Rights Campaign Healthcare Equality Index: 6 th year in a row that Vanderbilt University Medical Center was a Leader in LGBTQ Healthcare Equality.
Independently oversee research projects and perform near to totally independent research.
Supervise, plan, design and implement research projects
Establish protocol(s); define data collection, evaluation, and analysis procedures
Exercise discretion and independent judgment to develop methods and procedures for operation of complex scientific equipment
Supervise set-up and operation of various scientific experiments involving complex apparatus and equipment
Contribute to research to merit serving as author or co-author on research publications, etc.
Develop and apply bioinformatics tools to process, analyze, and interpret high throughput datasets, including DNA-seq, RNA-seq, ChIP-seq and single cell RNA-seq.
Assist principal investigator in preparation of grant applications and contract proposals
Apply biological and statistical knowledge to draw rigorous, actionable conclusions form complex data sets.
Communicate findings internally and externally.
Collaborate with groups across the institution to support research projects.
Participate in the preparation of written reports and oral presentations summarizing data analysis results, including detailed description of bioinformatics methods, detailed analysis of results, and synthesis of conclusions from summary tables.
Take initiative to acquire new bioinformatics, statistical or programming skills as needed.
Present research findings as needed
Responsible for plan and coordination of literature and library searches and data collection programs
Develop reports of results, graphs, charts, tables, etc. of research findings
Supervise writing, reviewing, and editing of various materials for publication
Provide supervisory responsibility to staff
Train and supervise technical staff, medical and graduate students
Provide technical guidance to students, post-doctoral fellows and faculty as required
Make recommendations to principal investigator regarding staff, supply and equipment needs for research projects
Maintain open communication between department and others
Open contact as needed with principal investigator, collaborating professionals,
Bachelor's Degree (or equivalent experience) and 7 years experience
Masters or higher (Preferred)
Preferred experience and skills:
Proficient with R or python, and experience in the Unix/Linux environments.
Proficiency in creating, modifying, and maintaining Unix scripts (shell/perl/python) to perform database management and analysis in parallel.
Familiarity with bioinformatics software packages, such as STAR, BWA, DESEQ2, Bioconductor, GSEA, samtools, etc.
Vanderbilt University Medical Center is home to Vanderbilt University Hospital, The Monroe Carell Jr. Children’s Hospital at Vanderbilt, the Vanderbilt Psychiatric Hospital and the Vanderbilt Stallworth Rehabilitation Hospital. These hospitals experienced more than 61,000 inpatient admissions during fiscal year 2015. Vanderbilt’s adult and pediatric clinics treated nearly 2 million patients during this same period. Vanderbilt University Hospital and the Monroe Carell Jr. Children’s Hospital at Vanderbilt are recognized again this year by U.S. News & World Report’s Best Hospitals as among the nation’s best with 18 nationally ranked specialties. Vanderbilt University Medical Center is world renowned because of the innovation, work ethic and collegiality of its employees. From our health care advances to our compassionate care, Vanderbilt owes its accomplishments and reputation to staff and faculty who bring skill and drive and innovation to the medical center day after day. World-leading academic departments and comprehensive centers of excellence pursue scientific discoveries and transformational educational and clinical advances across the entire spectrum of health and disease.As t...he largest employer in middle Tennessee, we welcome those who are interested in ongoing development in a caring, culturally sensitive and professional atmosphere. Most of us spend so much of our lives at work, we want to be part of maintaining a workplace in which people support one another and encourage reaching for excellence. Many high-achieving employees stay at Vanderbilt because of the professional growth they experience and because of their appreciation of Vanderbilt’s benefits, public events and discussions, athletic opportunities, beautiful setting and, above all, sense of community and purpose.Vanderbilt and its employees share a set of mutual expectations that have been created with productivity, legality, fairness and safety always in mind. We believe that our investment in training and compensating employees multiplies in value when we enable individuals to deliver their best performance for the benefit of us all.